Pauls Life Circle

About Tuberous Sclerosis

Tuberous Sclerosis is a rare genetic and neurological disease with an estimated 50,000 people with the disease in the U.S.A. It can cause tumors in the brain, kidneys, heart, lungs, eyes, and skin. This can lead to hard-to-control seizures, developmental disabilities, autism, speech and language dysfunction, learning, sleep and behavior disorders and other complications. It can be like having several cancers, kidney disease, epilepsy, autism, and mental disabilities all combined in one person.

Download more information on Tuberous Sclerosis

Recent Studies and Trials

Recent studies show that Adjunctive Everolimus Therapy is found to reduce seizures in Tuberous Sclerosis Complex.
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Download the article and results of the EXIST-3 Study

Download the results of the EXIST-1 Study



About TSC Clinic at Cincinnati Children's

Founded in 1992 by David Franz, MD, the TSC Clinic at Cincinnati Children's Hospital has grown to become the largest clinic in the world providing comprehensive, multidisciplinary medical care and social support for TSC children and adults. The clinic started and continues to be dedicated to improving quality of life and achieving best possible treatment outcomes for TSC patients.

Darcy A. Krueger, MD, PhD, Associate Director of Research, Division of Neurology, and the team at the TSC Clinic of Cincinnati Children's, proudly supports Paul's Life Circle.

If your child, or someone you know, has Tuberous Sclerosis, Cincinnati Children's can help. Read more >

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Paul's Life Circle, LLC
209 Eagleview Way
Cincinnati, OH 45215